Solvent



Patented Nov. 8, 1927.

UNITED STATES P TENT OFFICE. A

aosnn'r 0. 1111.2, on em. mm,

SOLVENT.

Drawing; I

. The object of this invention is to provide a solvent to be used as a substitute for grain alcohol in extracting the active principles from crude drugs, or in otherwise forming solutions, tinctures, and the like.

The improved solvent is composed of isopropyl alcohol, gCH CH(OI-I -OH acetic acid (0 H, 2 or CH,C OH), a suitable flavor, such as apple oil, (amyl but rate, and other esters compounded), and water (H O). These ingredients are combined in the following proportions by volume:

Isopropyl alcohol, 60%; acetic acid, 3%;

apple oil, 2%; and water, approximately I have found that a solvent formed according to the above formula will, 1n the vast majority of cases,- act as an efiicientsubstitute for alcohol in the extraction of the active principles from crude drugs, in the production of medicinal preparations, and in various ways in which alcohol is used in forming solutions. The secondary alcohol I employ is, alone, not as efficient in making extractions as grain alcohol, but I have found the the addition of a small amount of acetic aci will increase its power in this respect, owing to the well-known ropert possessed by acetic acid of dissolving var ous organic ubstances. When the seconds; alcohol an acetic acid are diluted water, the resultant mixture has about the Application filed September 11, 1926. Serial m.1s4,945.

same toxicity as grain alcohol, and the mixture is, in most cases, equallyeficient, and in many cases, more efficient than the grain alcohol when used as a solvent for drugs.

The flavoring ingredient, preferably apple oil, counteracts the flavor lmparted to the mixture by the acetic acid. So far as I have been able to determine, there is no difference in the aroma between solutions or extracts prepared with the use of my solvent aiidhtliose prepared with the use of grain a co 0 A distinct advanta e of my improvedsol- I vent is the fact that it is not subject to the ef the acetic acid.

' in testimony whereof, I have hereunto my hand.

RGBERT C. LULY. 

